Cymbalta with bipolar disorder were more likely to continue with their medications after 2 years.
Dr. Peter Breggin, lead author of the study, said that findings have practical implications for pharmacists, including the need to make sure they refer patients for follow-up and visits with clinical staff. "It is important for pharmacists to understand the risks and dangers associated with switching from medication to benzodiazepines," said Breggin, chief of the division geriatrics at University of Utah School Medicine.
In 2012, 1 7 individuals living with bipolar disorder were taking a mood stabilizer for longer period than 1 year. That has increased to 1 in 8 2017.
The study was published online February 12, 2017 in the Journal of Clinical Psychiatry.
The study identified 1,636 patients who were eligible for the study of patients between September 2011 and 2016 at four hospitals in the Salt Lake City, Utah metropolitan area. Their physicians provided informed consent and completed a medical record check.
There were 1,032 patients who on lithium or valproate and also taking other psychotropic medications for at least 2 years. There were 1,016 who on lithium only. There were 1,026 who on a mood stabilizer and stabilizers other than lithium or valproate.
The average age of patients was 50, with 81 percent in their 20s. Sixty-seven of patients had at least one lifetime diagnosis of psychiatric precio cymbalta 60 mg mexico illness and 58 percent had a lifetime treatment history. Of patients aged 55 to 64 years, 42 percent had a lifetime diagnosis of mental illness.
In the study, 17.9 percent of lithium users received maintenance treatment and 12.7 percent switched to another medication.
"After 2 years, the percentage of patients who switched from lithium to another medication was 21 percent," Breggin said. "The other medications had no statistically significant effect in terms of switching from lithium to another medication."
At 2 years, 46.6 percent of the lithium users continued taking Cymbalta 120 Pills 40mg $415 - $3.46 Per pill their medications, while 40.8 percent switched to another medication and 2.0 percent discontinued therapy completely.
After the first year, 78.8 percent of patients switched from lithium to another medication, but 6.9 percent continued with their prior medication and the remaining 24.2 percent discontinued all their medication.
Breggin pointed out, "Because there is a considerable amount of variability in treatment and follow-up among these samples. The most likely explanation is that Duloxetine available in us patients who switch from lithium to another medication are more likely to have a history of psychiatric illness. Many patients may be taking a cocktail of agents in an attempt to control their symptoms. If a physician is treating their medication-resistant, bipolar symptoms with medication alone, it may be more difficult to treat the patient with another medication."
The study included both men and women. There was no significant difference between the genders in results compared with men. Breggin said the number of female patients was sufficient to achieve a reliable outcome.
Breggin said while there isn't conclusive evidence.
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